Table 4 Analysis of the 8 studies stratified by the EBV detection method
From: Association between Epstein-Barr virus and Thymic epithelial tumors: a systematic review
Detection method | No. of studies | Events | Sample size | Point estimates of event rates (FE) | Point estimates of event rates (RE) | Homogeneity (Cochran’s Q) | I 2 1 | Homogeneity (p-value) | ||
|---|---|---|---|---|---|---|---|---|---|---|
Point estimate | 95% CI | Point estimate | 95% CI | |||||||
ISH | 5 | 18 | 133 | 0.06 | 0.02–0.12 | 0.14 | 0–0.57 | 111.55 | 96.4 | < 0.0001 |
Other | 3 | 18 | 46 | 0.32 | 0.19–0.47 | 0.33 | 0–0.84 | 10.34 | 92 | < 0.0001 |
Summary | 8 | 36 | 179 | 0.11 | 0.07–0.17 | 0.20 | 0–0.54 | 152.8 | 95.4 | < 0.0001 |
Total within (FE) | 136.51 | < 0.0001 | ||||||||
Total between (FE) | 15.29 | < 0.0001 | ||||||||
Total between (RE) | 0.41 | 0.5233 | ||||||||