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Table 2 Analysis of the 15 studies stratified according to EBV detection method

From: Association between Epstein-Barr virus and Thymic epithelial tumors: a systematic review

Detection methodNo. of studiesEventsSample sizePoint estimates of event rates (FE)Point estimates of event rates (RE)Homogeneity (Cochran’s Q)I 2 1Homogeneity (p-value)
Point estimate95% CIPoint estimate95% CI
ISH122243600–0.020.050–0.17144.0392.4< 0.0001
Other318460.320.19–0.470.330–0.8424.9692< 0.0001
Summary15404720.020.01–0.030.080.01–0.21206.7393.2< 0.0001
Total within (FE)       168.99 < 0.0001
Total between (FE)       37.74 < 0.0001
Total between (RE)       1.69 0.1931
  1. FE, fixed-effects model; RE, random-effects model. EBV, human papillomavirus; ISH, in situ hybridization
  2. 1 Only calculated for the fixed-effects model