Table 2 Analysis of the 15 studies stratified according to EBV detection method
From: Association between Epstein-Barr virus and Thymic epithelial tumors: a systematic review
Detection method | No. of studies | Events | Sample size | Point estimates of event rates (FE) | Point estimates of event rates (RE) | Homogeneity (Cochran’s Q) | I 2 1 | Homogeneity (p-value) | ||
|---|---|---|---|---|---|---|---|---|---|---|
Point estimate | 95% CI | Point estimate | 95% CI | |||||||
ISH | 12 | 22 | 436 | 0 | 0–0.02 | 0.05 | 0–0.17 | 144.03 | 92.4 | < 0.0001 |
Other | 3 | 18 | 46 | 0.32 | 0.19–0.47 | 0.33 | 0–0.84 | 24.96 | 92 | < 0.0001 |
Summary | 15 | 40 | 472 | 0.02 | 0.01–0.03 | 0.08 | 0.01–0.21 | 206.73 | 93.2 | < 0.0001 |
Total within (FE) | 168.99 | < 0.0001 | ||||||||
Total between (FE) | 37.74 | < 0.0001 | ||||||||
Total between (RE) | 1.69 | 0.1931 | ||||||||