Table 1 IARC criteria for oncogenicity for six oncoviruses with HHV-6 comparison
| Criteria | Characteristics | EBV | HTLV-1 | HHV-8 | HPV | HBV | HCV | HHV-6 |
|---|---|---|---|---|---|---|---|---|
| Major criteria | Viral detection (diffuse) | X | X | X | X | X | ||
| Tumor prevention (by antiviral vaccine) | a+/− | X | ||||||
| Minor criteria | Serology | X | X | X | X | X | X | |
| Viral detection (restricted) | N/A | N/A | N/A | N/A | N/A | X | ||
| Biological gradients | X | X | X | X | X | |||
| Clustering | X | X | X | X | b+/− | |||
| Medical interventions | X | X | X | X | ||||
| Animal models | X | X | X |