Skip to main content

Table 1 IARC criteria for oncogenicity for six oncoviruses with HHV-6 comparison

From: An evaluation of HHV-6 as an etiologic agent in Hodgkin lymphoma and brain cancer using IARC criteria for oncogenicity

Criteria

Characteristics

EBV

HTLV-1

HHV-8

HPV

HBV

HCV

HHV-6

Major criteria

Viral detection (diffuse)

X

X

X

X

X

  

Tumor prevention (by antiviral vaccine)

   

a+/−

X

  

Minor criteria

Serology

X

X

X

X

X

X

 

Viral detection (restricted)

N/A

N/A

N/A

N/A

N/A

 

X

Biological gradients

X

X

X

 

X

X

 

Clustering

 

X

X

 

X

X

b+/−

Medical interventions

   

X

X

X

X

Animal models

X

X

  

X

  
  1. aVaccine reduces number of precancerous lesions [51]
  2. bSome evidence supports clustering of HHV-6 [70, 71]
Back to article page

Infectious Agents and Cancer

ISSN: 1750-9378

Contact us