Skip to main content
Fig. 2 | Infectious Agents and Cancer

Fig. 2

From: CRISPR/Cas9-mediated LMP1 knockout inhibits Epstein-Barr virus infection and nasopharyngeal carcinoma cell growth

Fig. 2

Dependence of eukaryotic translation initiation factor 4E on the LMP1-mediated regulation on CNE-2 cell growth. a: Growth curves of the four groups of CNE-2 cells incubated for 24, 48, and 72 h. b: Relative eIF4E mRNA levels in LMP1-overexpressing CNE-2 cells after the eIF4E knockdown. c and d: Colony formation and colony size for LMP1-overexpressing CNE-2 cells after the eIF4E knockdown. Scramble RNA, negative control for siRNA-eIF4E; siRNA-eIF4E: eIF4E-specific siRNA. Each result was repeated independently in triplicate. *p < 0.05; ***p < 0.001; ****p < 0.0001; ns, no significance

Back to article page