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Fig. 1 | Infectious Agents and Cancer

Fig. 1

From: CRISPR/Cas9-mediated LMP1 knockout inhibits Epstein-Barr virus infection and nasopharyngeal carcinoma cell growth

Fig. 1

LMP1 overexpression regulates CNE-2 cell growth. a and b: Real-time quantitative PCR analysis (a) and western blotting (b) of mRNA and protein levels of LMP1, LMP2A, and eIF4E in the control, LMP1-overexpressing, LMP2A-overexpressing or both LMPs-overexpressing CNE-2 cells; c and d: Colony formation and colony size for CNE-2 cells after 3 days of incubation, measured via colony forming assays. Up control, control; LMP1 up, LMP1-overexpressed; LMP2A up, LMP2A-overexpressed; LMP1&LMP2A up, both LMP1- and LMP2A overexpressed. Each result was repeated independently in triplicate. ***p < 0.001; ****p < 0.0001; ns, no significance

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