Fig. 6

Histological and immuno-histochemical analysis with Ki67 on tumor sections of the xenograft mouse model of fibrosarcoma. a-b. Long and short interlacing streams and bundles of spindle cells are separated by the fibromatous matrix. Cells have indistinct borders, a slightly eosinophilic fibrillar cytoplasm and oval to fusiform nuclei with finely stippled chromatin. Hematoxylin and eosin, original magnification 10x for A (PRP-treated group) and 20x for B (controls). c-d Ki67 immunostaining in the PRP-gel-treated group (c) and group control (d). Hematoxylin counterstain, original magnification 10x