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Table 4 Positive predictive value, by self-reported HIV infection status, of detecting hrHPV E6/E7 mRNA for the presence of CIN 2+ among women from two rural districts of Uganda participating in a community-based study of cervical cancer screening

From: Prevalence, correlates, and predictive value of high-risk human papillomavirus mRNA detection in a community-based cervical cancer screening program in western Uganda

hrHPV Type Detected HIV-infectedb Participants HIV-uninfected Participants HIV-untested Participants All Participants
Total No. No. with CIN 2+ Positive predictive value % (95% CI) Total No. No. with CIN 2+ Positive predictive value % (95% CI) Total No. No. with CIN 2+ Positive predictive value % (95% CI) Total No. No. with CIN 2+ Positive predictive value% (95% CI)
Any hrHPV 42 4 9.8% (2.7 to 23%) 193 12 6.3% (3.3 to 11%) 20 5 25% (8.7 to 49%) 255 21 8.2% (5.1 to 12%)
At least one of HPV-16, 18 and 45a 10 1 10% (0.25 to 45%) 43 4 9.5% (2.7 to 23%) 5 4 80% (28 to 99%) 58 9 15% (7.3 to 27%)
HPV-16a 4 0 0% (0 to 60%) 28 3 11% (2.3 to 28%) 2 2 100% (16 to 100%) 34 5 15% (5.0 to 31%)
HPV-18 and/or 45a 7 1 14% (0.36 to 58%) 16 1 6.3% (0.15 to 30%) 3 2 67% (9.4 to 99%) 26 4 15% (4.4 to 35%)
At least one of HPV-31, 33, 35, 39, 51, 52, 56, 58, 59, 66 and 68 but without 16, 18 and 45 32 3 9.1% (1.9 to 24%) 150 8 29% (22 to 37%) 15 1 13% (1.7 to 40%) 197 12 6.1% (3.2 to 10%)
  1. amay also include HPV-31, 33, 35, 39, 51, 52, 56, 58, 59, 66 and 68
  2. bHIV infection status ascertained by self-report