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Table 3 Evaluation of potential independent correlates of hrHPV E6/E7 mRNA-positivity among Ugandan women participating in a community-based study of cervical cancer screening. Separate analyses are shown for correlates of any hrHPV type and for a restricted set of HPV 16 or 18/45

From: Prevalence, correlates, and predictive value of high-risk human papillomavirus mRNA detection in a community-based cervical cancer screening program in western Uganda

Characteristic

Any hrHPV Type

Prevalence Ratio (95% CI)

HPV 16 or 18/45

Prevalence Ratio (95% CI)

Unadjusted

P value

Adjusted

P value

Unadjusted

P value

Adjusted

P value

Age, per additional yeara

0.97 (0.96 to 0.99)

< 0.001

0.97 (0.96 to 0.99)

< 0.001

1.20 (0.92 to 1.58)

0.18

0.96 (0.92 to 0.99)

0.024

Marital statusb

 Never married

Ref.

 

Ref.

 

Ref.

 

Ref.

 

 Married

0.71 (0.45 to 1.13)

0.15

0.87 (0.50 to 1.52)

0.50

1.15 (0.28 to 4.55)

0.84

1.19 (0.30 to 4.74)

0.81

 Separated/divorced/widowed

0.96 (0.59 to 1.57)

0.17

1.02 (0.56 to 1.85)

0.95

1.36 (0.32 to 5.81)

0.68

1.30 (0.29 to 5.76)

0.73

Educational levelc

 None

Ref.

 

Ref.

 

Ref.

 

Ref.

 

 As least some primary

1.28 (0.97 to 1.69)

0.079

1.17 (0.86 to 1.58)

0.32

0.94 (0.51 to 1.73)

0.84

0.73 (0.38 to 1.38)

0.33

 At least some secondary

1.39 (1.01 to 1.91)

0.041

1.12 (0.78 to 1.63)

0.52

1.58 (0.82 to 3.08)

0.17

0.99 (0.46 to 2.14)

0.98

 At least some tertiary

1.68 (0.77 to 3.69)

0.19

1.36 (0.58 to 3.17)

0.48

2.64 (0.64 to 10.4)

0.17

1.69 (0.35 to 8.10)

0.51

Occupationd

 Unemployed

Ref:

 

Ref:

 

Ref.

 

Ref.

 

 Non-professional

1.17 (0.89 to 1.56)

0.26

1.08 (0.79 to 1.46)

0.63

1.64 (0.90 to 2.99)

0.11

1.35 (0.68 to 2.67)

0.39

 Professional

1.44 (1.12 to 1.84)

0.004

1.33 (0.98 to 1.80)

0.068

2.13 (1.25 to 3.63)

0.005

1.56 (0.77 to 3.15)

0.21

Pregnancy statuse

 Not pregnant

Ref.

 

Ref.

 

Ref.

 

Ref.

 

 Pregnant

1.31 (1.02 to 1.69)

0.036

1.37 (1.04 to 1.80)

0.026

1.14 (0.60 to 2.17)

0.69

1.30 (0.67 to 2.52)

0.43

HIV infection statusf

 HIV-uninfected

Ref.

 

Ref.

 

Ref.

 

Ref.

 

 HIV-infected

2.07 (1.67 to 2.57)

< 0.001

2.20 (1.74 to 2.78)

< 0.001

2.62 (1.57 to 4.38)

< 0.001

3.08 (1.77 to 5.35)

< 0.001

  1. aAge was adjusted for education, HIV infection status, marital status, pregnancy, and occupation
  2. bMarital status was adjusted for age, education, HIV infection status, pregnancy, and occupation
  3. cEducation was adjusted for age, HIV infection status, marital status, pregnancy, and occupation
  4. dOccupation was adjusted for age, education, HIV infection status, marital status, and pregnancy
  5. ePregnancy was adjusted for age, education, HIV infection status, marital status and occupation
  6. fHIV infection status was adjusted for age, education, marital status, pregnancy, and occupation
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Infectious Agents and Cancer

ISSN: 1750-9378

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