Association of HLA-G 3′ UTR polymorphism and expression with the progression of cervical lesions in human papillomavirus 18 infections

Table 1 Study Participant Characteristics

Characteristic	Controls	HPV16 group	HPV18 group
Characteristic	(n = 185)	(n = 130)	(n = 130)
Age at screening, years
Median	40.8 ± 8.0	41.3 ± 10.0	41.0 ± 9.8
Range	18–69	20–71	21–72
HPV status
HPV negative	185	0	0
HPV16 positive	0	130	0
HPV18 positive	0	0	130
Cytology
NILM	185	40(52.6)	89(88.1)
ASCUS	0	10(13.2)	5(5.0)
ASC-H	0	11(14.5)	4(4.0)
LSIL	0	12(15.8)	3(3.0)
HSIL	0	3(3.9)	0(0.0)
Histology diagnosis
Normal/Cervicitis	–	24(27.9)	50(74.6)
CIN1	–	10(11.6)	11(16.4)
CIN2	–	15(17.4)	1(1.5)
CIN3	–	31(36.0)	3(4.5)
SCC	–	6(7.0)	0(0.0)
ADC	–	0(0.0)	2(3.0)

Abbreviations, HPV human papillomavirus, NILM negative for intraepithelial lesion or malignancy, ASCUS atypical squamous cells of undetermined significance, ASC-H atypical squamous cells and cannot exclude high-grade squamous intraepithelial lesions, LSIL low-grade squamous intraepithelial lesions, HSIL high-grade squamous intraepithelial lesions, CIN cervical intraepithelial neoplasia, SCC squamous cell carcinoma, ADC adenocarcinoma

ISSN: 1750-9378