Table 6 Frequency of PIK3CA mutations identified in patients with esophageal squamous cell carcinoma worldwide
References | Year | Country (Region) | Patients of study | PIK3CA mutated (%) | Type of sample | Techniques |
|---|---|---|---|---|---|---|
Mori et al. [24] | 2008 | Japan | 88 | 2.2% | FT | Direct Sequencing |
Wang et al. [30] | 2013 | China | 76 | 3.9% | FT | Direct Sequencing |
Akagi et al. [17] | 2009 | Japan | 52 | 7.7% | FFPE | Direct Sequencing |
Kim et al. [21] | 2016 | Korea | 534 | 10.5% | FFPE | Direct Sequencing |
Phillips et al. [25] | 2006 | Australia | 35 | 11.8% | FFPE | Direct Sequencing |
Zheng et al. [33] | 2016 | China | 79 | 19.7% | FT | Pyrosequencing |
Shigaki et al. [27] | 2013 | China | 219 | 21.0% | FT | Pyrosequencing |
Liu et al. [23] | 2017 | China | 210 | 22.9% | FFPE | Pyrosequencing |
Baba et al. [18] | 2015 | Japan | 440 | 23.0% | FFPE | Pyrosequencing |
Yang et al. [31] | 2017 | China | 24 | 4.2% | FFPE | NGS |
Song et al. [28] | 2014 | China | 158 | 4.5% | FT | NGS |
Lin et al. [22] | 2014 | China | 139 | 7.0% | FFPE | NGS |
Gao et al. [19] | 2014 | Japan | 133 | 9.0% | FT | NGS |
Sawada et al. [26] | 2016 | Japan | 144 | 10.4% | FT | NGS |
TCGA et al. [9] | 2017 | Western and Eastern | 90 | 13.0% | FT | NGS |
Yokota et al. [37] | 2018 | Japan | 126 | 13.5% | FFPE | NGS |
Zhang et al. [32] | 2015 | China | 90 | 17.0% | FT | NGS |
Wang et al. [29] | 2015 | USA | 71 | 24.0% | FFPE | NGS |