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Table 2 Frequency of PIK3CA mutations in the three study groups

From: PIK3CA mutations are frequent in esophageal squamous cell carcinoma associated with chagasic megaesophagus and are associated with a worse patient outcome

Variable

 

Groups (n = 89)

 

Category

CM/ESCC (n = 23)

ESCC (n = 38)

CM (n = 28)

p-value

PIK3CA gene

WT

18 (78.3%)

34 (89.5%)

27 (96.4%)

0.132**

MUT

5 (21.7%)

4 (10.5%)

1 (3.6%)

  1. **Fisher’s exact test. CM/ESCC – chagasic megaesophagus associated with esophageal squamous cell carcinoma; ESCC – esophageal squamous cell carcinoma without chagasic megaesophagus; CM – chagasic megaesophagus without esophageal squamous cell carcinoma. WT – wild-type; MUT – mutant; N – number of cases
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Infectious Agents and Cancer

ISSN: 1750-9378

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