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Table 2 Frequency of PIK3CA mutations in the three study groups

From: PIK3CA mutations are frequent in esophageal squamous cell carcinoma associated with chagasic megaesophagus and are associated with a worse patient outcome

Variable   Groups (n = 89)  
Category CM/ESCC (n = 23) ESCC (n = 38) CM (n = 28) p-value
PIK3CA gene WT 18 (78.3%) 34 (89.5%) 27 (96.4%) 0.132**
MUT 5 (21.7%) 4 (10.5%) 1 (3.6%)
  1. **Fisher’s exact test. CM/ESCC – chagasic megaesophagus associated with esophageal squamous cell carcinoma; ESCC – esophageal squamous cell carcinoma without chagasic megaesophagus; CM – chagasic megaesophagus without esophageal squamous cell carcinoma. WT – wild-type; MUT – mutant; N – number of cases