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Table 1 Baseline characteristics: biodata, clinical and laboratory profile of the study patients and controls

From: Risk factors for liver Cancer in HIV endemic areas of Western Kenya

Parameter Cases–N=257 (Range/%) Controls –N=257 (Range/%) P–value
Age (years) mean ± SD 46.2 ± 25.1 (range 15-80) 37.41 ± 14.9 (22-58) <0.0001
CD4+ cell (350-1600) /μl 237.7 ± 96.4 [range 50-417] 626.3 ± 102.32 (409-910) <0.0001
ALT (5-37 IU/L) Mean ±SD 193.5 ± 215.9 [range 2.9-1327] 40.1 ± 2.3 (2-57) <0.0001
AST (5-40 IU/L) Mean ±SD 173.0 ± 142 [range 14-600] 36.2 ± 7.8 (3-51) <0.0001
α-FP (0-9ng/ml) Mean ±SD 14,205 ± 58,299[0.5-433,879] 5 ± 2.9 (0-8) <0.0001
INR (0.67-1.01) Mean ±SD 1.6 ± 0.5 [range 1.0-2.9] 0.9 ± 0.2 (0.5-1.01) <0.0001
Aflatoxins(1.0-5.0 ppb) 28.35 ppb [2(0.77%)] 0 N/A
BMI (kg/m2) Mean ±SD 21.6 ± 3.1 (range 17.64 – 33.87) 20.7 ± 2.3 (59-82) 0.667
HBV mono-infection 40 (15.6%) 179 (69.6%) <0.0001
HCV mono-infection 1 (0.38%) 0 N/A
HIV mono-infection 51 (19.8%) 28 (10.9%) 0.3097
HBV/HIV co-infection 58 (22.6%) 0 N/A
HCV/HIV co-infection 0 0 N/A
HCC No risk factor or HIV 93 (36.1%) 10 (3.4%) 0.0365
Excess alcohol intake 7 (2.7%) 21(8.2) 0.6173
Positive family history (genetic) of HCC 5 (2%) 0 N/A