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Table 2 Characteristics of Children and Adolescents with Endemic KS in Context of a Pediatric-Specific Staging Classification

From: Endemic Kaposi sarcoma in HIV-negative children and adolescents: an evaluation of overlapping and distinct clinical features in comparison with HIV-related disease

 

Stage 1: Mild/Moderate Cutaneous/Oral KS

Stage 2: Lymphadenopathic KS

Stage 3: Woody Edema KS

Stage 4: Visceral and/or Disseminated Cutaneous/Oral KS

Number of patients, n

4

6

6

4

Baseline Anemia (hgb < 8), n (%)

0

5 (83%)

1 (17%)

3 (75%)

Baseline Thrombocytopenia (platelet count < 100), n (%)

1 (25%)

4 (67%)

0

3 (75%)

Alive in complete remission, n (%)

3 (75%)

5 (83%)

1 (17%)

0

Alive with stable disease, n (%)

0

0

3 (50%)

1 (25%)

Deaths, n (%)

1 (25%)

1 (17%)

2 (33%)

3 (75%)

 KS related death

0

1

2

3

 Non-KS related death

1

0

0

0

2-year EFS in HIV+ KS cohorta

too few patients to determine

73%

29%

0

2-year OS in HIV+ KS cohorta

75%

79%

12%

  1. Legend: KS Kaposi sarcoma, hgb hemoglobin, EFS event-free survival, OS overall survival, areferences the published historical HIV-related pediatric KS cohort (reference number 17)