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Table 1 Expression of HPV-induced p16INK4A and prevalence of HPV and EBV in squamous cell carcinoma according to primary tumor site and histotype

From: Human papillomavirus (HPV) and Epstein-Barr virus (EBV) in keratinizing versus non- keratinizing squamous cell carcinoma of the oropharynx

  HPV-induced p16INK4A HPV+
(%)
EBV+ (%) Co-infection HPV-EBV (%)
Primary site (No.)     
OPSCC (40) 11 (27.5) 10 (25) 18 (45) 4 (10)
OSCC (11) 1 (9.1) 8 (72.7)
Histotype (No.)     
NKSCC (26) 11 (42.3) 9 (34.6) 16 (61.5) 4 (15.4)
KSCC (25) 1 (4) 1 (4) 10 (38.5)
  1. KSCC keratinizing squamous cell carcinoma, NKSCC nonkeratinizing squamous cell carcinoma. HPV p16 detected by immunohistochemistry (IHC)