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Table 1 Expression of HPV-induced p16INK4A and prevalence of HPV and EBV in squamous cell carcinoma according to primary tumor site and histotype

From: Human papillomavirus (HPV) and Epstein-Barr virus (EBV) in keratinizing versus non- keratinizing squamous cell carcinoma of the oropharynx

 

HPV-induced p16INK4A

HPV+

(%)

EBV+ (%)

Co-infection HPV-EBV (%)

Primary site (No.)

    

OPSCC (40)

11 (27.5)

10 (25)

18 (45)

4 (10)

OSCC (11)

1 (9.1)

8 (72.7)

Histotype (No.)

    

NKSCC (26)

11 (42.3)

9 (34.6)

16 (61.5)

4 (15.4)

KSCC (25)

1 (4)

1 (4)

10 (38.5)

  1. KSCC keratinizing squamous cell carcinoma, NKSCC nonkeratinizing squamous cell carcinoma. HPV p16 detected by immunohistochemistry (IHC)