Skip to main content

Table 3 Direct costs of the management of each type on lesion in Spain reported in the literature and use of resources considered

From: Epidemiologic and economic burden of HPV diseases in Spain: implication of additional 5 types from the 9-valent vaccine

Lesion [sources]

Cost (2017 €)

Use of resources

Genital warts [11]

1036€

Visits with specialists, diagnosis tests, pharmacological and other treatments and hospitalizations.

CIN 2/3 [14]

CIN2:2022€

Visits with gynecologists, diagnosis tests, pharmacological, laser and surgical treatments, and medical complications.

CIN 3: 2600€

Cervical cancer [27]

8760€

Diagnosis (colposcopy, cytology, HPV DNA testing), treatment (LEEP/LLETZ, hysterectomy, conization, laser destruction, radiotherapy and chemotherapy)

Vulvar cancer [28]

12,994€

Direct cost of diagnosis, treatment and hospitalization

Vaginal cancer [28]

10,664€

Anal cancer (men) [29]

7790€

Direct costs of hospitalized patients based on Diagnosis-related groups

Anal cancer (women) [29]

7481€

Penile cancer [29]

7135€

Oral cavity cancer (men) [30]

7984€

Oral cavity cancer (women) [30]

8198€

Nasopharynx cancer (men) [30]

8086€

Nasopharynx cancer (women) [30]

6708€

Oropharynx cancer (other) (men) [30]

7373€

Oropharynx cancer (other) (women) [30]

7462€

Hypopharynx cancer (men) [30]

8213€

Hypopharynx cancer (women) [30]

7838€

Pharynx cancer (men) [30]

7478€

Pharynx cancer (women) [30]

8618€

Larynx cancer (men) [30]

8652€

Larynx cancer (women) [30]

9257€

  1. CIN: cervical intraepithelial neoplasia; DNA: deoxyribonucleic acid; HPV: human papillomavirus; LEEP: loop electrosurgical excision procedure; LLETZ: large loop excision on the transformation zone