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Table 2 Crude incidence rates and estimated number of new annual cases of genital warts, precancerous lesions and cancer in men and women in Spain

From: Epidemiologic and economic burden of HPV diseases in Spain: implication of additional 5 types from the 9-valent vaccine

Lesion [sources] ICD-10 Crude annual incidence rate per 100.000 men or women Estimated number of new annual cases in 2016 in Spain (95% CI)
Genital warts (men) [11] NA 136.60 31,163 (30,806–31,497)
Genital warts (women) [11] NA 99.60 23,560 (23,238–23,839)
CIN 2/3 [13,15] NA 142.02 33,594 (33,235–33,953)
VIN2/3 [13,15] NA 6.02 1424 (1350–1498)
VaIN 2/3 [13,15] NA 1.02 241 (210–271)
AIN 2/3 (men) [13, 16] NA 0.57 130 (108–153)
AIN 2/3 (women) [13, 16] NA 0.27 63 (47–78)
PIN 2/3 [13, 17] NA 1.32 302 (268–336)
Cervical cancer [13] C53 10.10 2389 (2293–2485)
Vulvar cancer [12, 13] C51 2.77 655 (556–754)
Vaginal cancer [12, 13] C52 0.47 111 (70–151)
Anal cancer (men) [12, 13] C21 0.86 197 (143–250)
Anal cancer (women) [12, 13] C21 0.68 160 (111–209)
Penile cancer [12, 13] C60 1.91 436 (356–516)
Oral cavity cancer (men) [12, 13] C02–06 7.55 1724 (1492–1955)
Oral cavity cancer (women) [12, 13] C02–06 0.64 736 (574–876)
Nasopharynx cancer (men) [12, 13] C11 1.54 352 (277–426)
Nasopharynx cancer (women) [12, 13] C11 0.45 106 (65–148)
Oropharynx cancer (men) [12, 13] C01, C09, C10 1.64 1066 (841–1290)
Oropharynx cancer (women) [12, 13] C01, C09, C10 0.10 152 (68–233)
Hypopharynx cancer (men) [12, 13] C12–13 3.62 826 (711–940)
Hypopharynx cancer (women) [12, 13] C12–13 0.25 59 (28–89)
Pharynx cancer (men) [12, 13] C14 1.05 240 (179–302)
Pharynx cancer (women) [12, 13] C14 0.13 32 (9–54)
Larynx cancer (men) [12, 13] C32 16.72 3815 (3569–4060)
Larynx cancer (women) [12, 13] C32 0.92 217 (158–276)
  1. 95% CI: 95% confidence interval; NA: not applicable; AIN: anal intraepithelial neoplasia; CIN: cervical intraepithelial neoplasia; HPV: human papillomavirus; ICD: International Classification of Diseases; PIN: penile intraepithelial neoplasia; VaIN: vaginal intraepithelial neoplasia; VIN: vulvar intraepithelial neoplasia