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Table 1 Clinical and virological characteristics of the patients

From: Quasispecies variant of pre-S/S gene in HBV-related hepatocellular carcinoma with HBs antigen positive and occult infection

  HBsAg-positive
HCC (n = 10)
OBI-related
HCC (n = 9)
P value
Age (years) 53.6 ± 11.5 69.7 ± 5.6 0.002*
Sex (male/female) 9/1 8/1 0.737
PLT (× 104/mm3) 17.9 ± 4.9 23.0 ± 8.4 0.131
AST (U/L) 59.1 ± 37.9 38.9 ± 15.0 0.145
ALT (U/L) 33.2 ± 11.0 31.4 ± 15.4 0.782
HbA1c (%) 5.29 ± 0.45 5.46 ± 0.50 0.461
HBsAg (mIU/ml) 3278 ± 3045 0  
Anti-HBc antibody (C.O.I.) 12.6 ± 1.8 10.1 ± 1.2 0.002*
HBV DNA (log copies/ml) 5.41 ± 1.84 < 2.06  
Hyaluronic acid (ng/ml) 62.7 ± 51.0 107.1 ± 123.2 0.338
Fibrosis (F0–2/F3–4) 4/6 4/5 0.605
Total reads (mean ± SD) 4,451,542 ± 2,357,824 3,708,797 ± 2,365,839 0.503
Mapping reads (mean ± SD) 1,075,698 ± 845,602 619,866 ± 347,934 0.144
Coverage (mean ± SD) 131,921 ± 97,014 77,279 ± 49,215 0.139
  1. *P < 0.05