Fig. 2From: Quasispecies variant of pre-S/S gene in HBV-related hepatocellular carcinoma with HBs antigen positive and occult infectionScheme of the HBV pre-S/S region including the functional domains. NCTP-binding site in the pre-S1 region plays an important role in viral recognition and entry into hepatocytes. The alpha determinant epitope domain in the pre-S2 is involved in HBsAg productionBack to article page