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Fig. 1 | Infectious Agents and Cancer

Fig. 1

From: T- and NK-cell populations with regulatory phenotype and markers of apoptosis in circulating lymphocytes of patients with CIN3 or microcarcinoma of the cervix: evidence for potential mechanisms of immune suppression

Fig. 1

Boxplots representing the frequencies of cells with CD4 Treg-related phenotype in peripheral blood of patients and healthy donors. Lymphocytes were selected based on FSC/SSC distribution, gated for CD4 and further discriminated according to CD25 and CD127/FoxP3 staining (shown in the upper left). Here and below, individual values are shown as dots. The lower and upper hinges correspond to the first and third quartiles (the 25th and 75th percentiles). The middle line corresponds to the second quartiles (median, 50th percentile). The upper whisker extends from the hinge to the largest value no further than 1.5 * IQR from the hinge (where IQR is the inter-quartile range, or distance between the first and third quartiles). The lower whisker extends from the hinge to the smallest value at most 1.5 * IQR of the hinge. Data beyond the end of the whiskers are called “outlying” points and are plotted individually. Significant differences between the patients and the controls are designated by asterisks: * p < 0.05, ** p < 0.01, *** p < 0.001 (U-test)

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