Infectious Agents and Cancer

Table 1 Baseline characteristics and risk factors of HCC and control group patients

From: Hepatitis C Virus (HCV) genotypes distribution among hepatocellular carcinoma patients in Southern Italy: a three year retrospective study

Characteristics	HCC (n = 152)		Control Group (n = 568)
	n.	%	n.	%
Male	105	69.1^A	320	56.4^A
Female	47	30.9	248	43.6
M/F ratio	2.23		1.30
Median BMI (range) kg/m²	26 (21–32)		25.5 (20–38)
Mean Age (range), years	73 (55–91)		65 (45–85)
< 50 years	2	1.3	107	18.9
50–70 years	73	48.0	261	45.9
> 70 years	77	50.7^B	200	35.2^B
Alcohol consumption^*	74	48.7	289	50.8
Cigarettes smoking^	60	39.5	201	35.4
Serum levels of AST (> 45 U/L)	94	61.8	352	61.9
Serum levels of ALT (> 45 U/L)	89	58.5	325	57.2
ALP levels (> 250 U/L)	71	46.7	261	45.9
Albumin levels (< 3.5 g/L)	81	53.3	280	49.2
Bilirubin levels (> 1.2 mg/dL)	91	59.8	301	52.9

^*Alcohol intake was considered only in case of consumption of 8 g/day by men and 6 g/day by women for at least 5 years
^ Cigarette consumption was considered significant if over 15 cigarettes/day for almost 5 years
^A = χ²:7.06; p < 0.01; OR: 1.72; 95% C.I = 1.15–2.58
^B = χ²:12.08; p < 0.001; OR: 1.88; 95% C.I = 1.31–2.71

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