High risk human papilloma viruses (HPVs) are present in benign prostate tissues before development of HPV associated prostate cancer

Table 3 HPV DNA identification in the TCGA series of prostate cancers

Sample ID	HPV type	E6	E7	E1	E2	E4	E5	L2	L1	Confidence
df64c493-d290-41c7-abd3-ab65cda57b02	16	8	12	5	37	24	16	2	0	High
5faf8ec8-f94c-4b0c-9d91-70942f15f3c8	16	3	5	8	50	28	14	0	0	High
b13d4e3d-898e-4339-a506-110b8e803b6e	16	6	9	1	18	10	5	0	0	High
2d8b33e3-002b-4592-9bc3-b3eab242c893	16	0	3	4	14	10	8	0	0	High
627b9ff8–2557-4470-824a-b76a8bcd1e9f	16	8	12	1	0	0	0	0	6	High
3ea3bcfc-2030-4d0b-b9b2-840a9ad1acaf	16	1	3	2	7	5	6	0	0	High
bccb7f9d-8dde-45b7-a50d-6c7233239ceb	18	3	4	12	0	0	0	0	0	High
7413d045-cedb-4ec6-95ea-6f7b676f800d	16	0	0	0	11	6	7	0	0	High
16,410,934-a686-4dbd-9086-bc060135f0b4	16	0	1	0	11	4	4	0	2	High
6c728891–8924-4a51-b3ed-f4b83d6c8de4	16	1	2	2	7	3	1	0	0	High
4da83354–4512-4dca-af59-dc8217363511	16	0	0	1	3	1	2	2	0	High
09bb6311-41ad-46a1–8195-6d1fdacd7cb0 ^a	16	0	4	0	0	0	0	0	0	High
ebb062c0-ea5b-48f6-aeee-2674b6dabdec^a,b	16	2	1	2	0	0	0	0	0	Med
dcceaf54-0bce-4650-9980-9843abce0c41^a	16	2	0	0	0	0	0	0	0	Med
f9160e70-27f0-4c8c-a667-b24195ad659c	16	0	2	0	0	0	0	0	0	Med
563e009c-c93d-46 cm³-867d-f5c89d9336d9	48	0	0	2	0	0		0	0	Med
1b59308e-48 cm³-4bd9-b990-c82154487522	4	0	0	2	0	0		0	0	Med
4cd7f57c-fd19-4def-a5fb-dca3dbc10320	16	1	3	2	5	4	0	0	0	Low
53ebd660-7f5d-433a-acb7-4153f36484d0	18	1	1	0	0	0	0	0	0	Low
aa0e444b-c913-4a70-a76d-be70ccf80691	96	0	0	0	0	0		1	0	Low

HPV types and genes (E6, E7, E1, E2, E4, E5, L2, L1) identified by Next Generation Sequencing. 0 indicates no reads. Of the 17 HPV 16/18 positive prostate cancer samples 14 (82%) had reads for the E7 gene
^amarks TGCA specimens with HPV reads from Tang et al. 2013
^bmarks normal tissue. Confidence is marked at high (both quality filters), Med (one quality filter), Low (no quality filters)

ISSN: 1750-9378