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Fig. 3 | Infectious Agents and Cancer

Fig. 3

From: High risk human papilloma viruses (HPVs) are present in benign prostate tissues before development of HPV associated prostate cancer

Fig. 3

Cytokeratin staining in benign and subsequent prostate cancer which developed in the same patient 2 years later. Panel a Benign prostate basal cells showing strong cytokeratin immunoreactivity (brown staining). Panel b Prostate cancer cells in the same patient showing weak and absent cytokeratin immunoreactivity. This pattern of changes in cytokeratin staining and absence of basal cells as prostate cancer develops is useful in the diagnosis of prostate cancer

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