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Fig. 2 | Infectious Agents and Cancer

Fig. 2

From: Whole-genome analysis of human papillomavirus genotypes 52 and 58 isolated from Japanese women with cervical intraepithelial neoplasia and invasive cervical cancer

Fig. 2

Phylogenetic tree based on the analyses of HPV58 whole-genome sequences of 48 isolates and 46 genomes available from GenBank (total 94 sequences). Phylogenetic analyses were conducted using the Maximum likelihood algorithm by RAxML with 1000 bootstrap replicates. The tree is drawn to scale, with branch lengths measured in the number of substitutions per site. The histological grades of cervical specimens from which the isolates were recovered are shown with colored ID numbers: blue, CIN1; green, CIN2/3; red, ICC

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