Fig. 4

Protein-protein interaction maps of Helicobacter pylori proteins associated with gastric diseases. a The STRING tool (http://string-db.org) was used for making the networks with all the proteins listed in Table 2. Confidence views are shown, where the thickness of the connecting lines indicates the level of confidence. Stronger associations are represented by thicker lines. Different colors indicate different biological processes: (i) blue (organic substance metabolic process); (ii) green (defense against extreme environment conditions); (iii) yellow (oxidation reduction); (iv) brown (chemical reactions involving various nitrogenous compounds), and (v) red (bacteria motility). b The STRING tool was used for making the networks with the H. pylori proteins up-regulated in gastric cancer versus duodenal ulcer, which were mainly involved in nucleic acid binding (red color)