Mouse mammary tumor-like virus (MMTV) is present in human breast tissue before development of virally associated breast cancer

Table 1 MMTV-like env gene sequences in benign breast tissues and subsequent breast cancer in the same patients

Patient	Age	Diagnosis	MMTV-like New York (ISMMS) by PCR	MMTV-like Pisa (UP) by PCR
1	36	Benign	neg	neg
1	41	IDC- NST	neg	neg
2	72	Benign		neg
2	75	DCIS- mucinous		neg
3	33	Benign	neg	neg
3	44	IDC/DCIS- NST	neg	neg
4	45	Benign	pos	neg
4	46	DCIS-cribriform	pos	neg
5	50	Benign	pos	neg
5	60	ILC-pleomorphic	pos	pos
6	62	Benign	neg
6	66	DCIS- micropapillary	neg
7	47	Benign	neg
7	56	IDC-NST	neg
8	49	Benign		neg
8	52	IDC- NST		neg
9	46	Benign	neg
9	53	IDC-NST	pos
10	48	Hyperplasia	pos
10	52	IDC-NST	pos
11	35	Benign		neg
11	46	IDC		neg
12	44	Benign	neg	neg
12	48	IDC-NST	neg	neg
13	67	Benign		neg
13	75	IDC-NST		neg
14	48	Benign	neg	neg
14	54	IDC-NST	neg	neg
15	42	Benign		neg
15	49	IDC-NST		pos
16	42	Benign		neg
16	48	IDC-NST		neg
17	39	Benign	neg
17	45	ILC	neg
18	53	Benign	neg
18	62	DCIS	pos
19	65	Benign		pos
19	67	IDC-NST		neg
20	39	Benign	neg
20	44	DCIS-comedo	neg
21	55	Benign		neg
21	62	IDC-NST		neg
22	37	Benign	neg	neg
22	39	IDC-cribriform, mucinous	neg	neg
23	39	Benign	pos	neg
23	42	DCIS-comedo	pos	neg
24	48	Benign	pos
24	54	DCIS-cribriform	pos
25	63	Benign	neg
25	67	IDC-NST	pos

IDC invasive ductal carcinoma, ILC invasive lobular carcinoma, DCIS ductal carcinoma in situ, NST no special type, pos positive, neg negative

ISSN: 1750-9378