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Table 5 Univariate and multivariate logistic regression analysis of risk factors for squamous intraepithelial lesion and high-grade squamous intraepithelial lesion

From: Human papillomavirus genotypes and HPV-16 variants distribution among Tunisian women with normal cytology and squamous intraepithelial lesions

Risk Factors

Risks for SIL

(n = 471)

Risks for HSIL

(n = 471)

Univariate analysis

Multivariate analysis

Univariate analysis

Multivariate analysis

SIL (%)

P

OR [95% CI]

HSIL (%)

P’

OR [95% CI]

HPV status

 HPV negative

3.9

 

1

2.6

 

1

 HPV positive

39.4

<10-6

14.10 [7.00–28.40]

22.5

<10-6

11.06 [4.61–26.56]

Years of sexual activity

  ≤ 10

10.3

  

4.8

  

  > 10

16.5

0.080

ni

11.6

0.020

ns

Menopausal status

 Non menopausal

12

 

1

6

 

1

 Menopausal

34.1

6.10-5

3.66 [1.62–8.29]

31.8

<10-6

7.30 [3.11–17.13]

  1. n, number; ns, not significant; ni, not included in the multivariate analysis; SIL, squamous intraepithelial lesion; HSIL, high-grade squamous intraepithelial lesion; p, probability for SIL; p’, probability for HSIL