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Table 5 Univariate and multivariate logistic regression analysis of risk factors for squamous intraepithelial lesion and high-grade squamous intraepithelial lesion

From: Human papillomavirus genotypes and HPV-16 variants distribution among Tunisian women with normal cytology and squamous intraepithelial lesions

Risk Factors Risks for SIL
(n = 471)
Risks for HSIL
(n = 471)
Univariate analysis Multivariate analysis Univariate analysis Multivariate analysis
SIL (%) P OR [95% CI] HSIL (%) P’ OR [95% CI]
HPV status
 HPV negative 3.9   1 2.6   1
 HPV positive 39.4 <10-6 14.10 [7.00–28.40] 22.5 <10-6 11.06 [4.61–26.56]
Years of sexual activity
  ≤ 10 10.3    4.8   
  > 10 16.5 0.080 ni 11.6 0.020 ns
Menopausal status
 Non menopausal 12   1 6   1
 Menopausal 34.1 6.10-5 3.66 [1.62–8.29] 31.8 <10-6 7.30 [3.11–17.13]
  1. n, number; ns, not significant; ni, not included in the multivariate analysis; SIL, squamous intraepithelial lesion; HSIL, high-grade squamous intraepithelial lesion; p, probability for SIL; p’, probability for HSIL