Skip to main content

Table 2 Hazard ratios (HR) with 95 % confidence intervals (CI) for hepatocellular carcinoma (HCC) among 4270a study subjects, according to HCV RNA-positivity and FIB-4 index. Naples, 2003–2012

From: Infection with hepatitis viruses, FIB-4 index and risk of hepatocellular carcinoma in southern Italy: a population-based cohort study

HCV RNA FIB-4 <1.45 FIB-4 1.45–3.25 FIB-4 >3.25
Subjects
No.
HCC cases
No. (%)
HRb (95 % CI) Subjects
No.
HCC cases
No. (%)
HRb (95 % CI) Subjects
No.
HCC cases
No. (%)
HRb (95 % CI)
Negative 3380 1 (0.03) 1* 604 0 (0.0) 0 (0-∞) 47 1 (2.1) 79.5 (4.9–1285)
Positive 61 0 (0.0) 0 (0-∞) 110 3 (2.7) 99.5 (10.3–957.3) 68 12 (17.6) 771.2 (100.0–5949)
  1. a99 HBsAg-positive and 89 anti-HCV-positive, HCV-RNA-negative study subjects were excluded. Information on FIB-4 index was not available for 34 remaining study subjects
  2. bHazard ratios adjusted for gender
  3. *Reference category