Skip to main content

Table 1 TNM Classification for anal cancer

From: Radiological assessment of anal cancer: an overview and update

Primary tumor (T)
 TX Primary tumor cannot be assessed
 T0 No evidence of primary tumor
 Tis Carcinoma in situ (Bowen disease, high-grade squamous intraepithelial lesion [HSIL], anal intraepithelial neoplasia II-III (AIN II-III)
 T1 Tumor 2 cm or less in greatest dimension
 T2 Tumor more than 2 cm but not more than 5 cm in greatest dimension
 T3 Tumor more than 5 cm in greatest dimension
 T4 Tumor of any size invades adjacent organ(s) (eg, vagina, urethra, bladder);direct invasion of the rectal wall, perirectal skin, subcutaneous tissue, or the sphincter muscle(s) is not classified as T4
Regional lymph nodes (N)
 NX Regional lymph nodes cannot be assessed
 N0 No regional lymph node metastasis
 N1 Metastasis in perirectal lymph node(s)
 N2 Metastasis in unilateral internal iliac and/or inguinal lymph node(s)
 N3 Metastasis in perirectal and inguinal lymph nodes and/or bilateral internal iliac and/or inguinal lymph nodes
Distant metastasis (M)
 M0 No distant metastasis
 M1 Distant metastasis