HPV-16 infection modifies overall survival of Puerto Rican HNSCC patients

Table 3 Multivariate Cox analysis

Covariate	Coefficient	Standard error	P value	HR value, 95 % CI
Positive nodal status	0.308	0.209	0.141	1.361 [0.903 – 2.052]
Tumor stage	0.034	0.099	0.733	1.034 [0.852 – 1.257]
Tumor grade
Well	0.089	0.442	0.841	1.093 [0.460 – 2.598]
Moderate	0.348	0.322	0.279	1.417 [0.754 – 2.662]
Poor	0.496	0.344	0.149	1.642 [0.837 – 3.222]
Tumor site
Larynx	- 0.170	0.337	0.614	0.844 [0.436 – 1.634]
Oral Cavity	- 0.176	0.350	0.616	0.839 [0.423 – 1.665]
Pharynx	0.237	0.423	0.575	1.267 [0.554 – 2.901]
Heavy smoking	0.202	0.329	0.539	1.224 [0.642 – 2.333]
Heavy drinking	0.217	0.249	0.384	1.242 [0.762 – 2.024]
HPV-16	0.555	0.182	0.002	1.742 [1.219 – 2.488]
Sex	- 0.247	0.324	0.447	0.781 [0.414 – 1.475]
Age	0.026	0.007	0.000	1.026 [1.011 – 1.041]

(−2 Log Likelihood): 1051.086, HR hazard ratio, 95 % CI 95 % confidence interval, HPV-16 human papillomavirus type 16

ISSN: 1750-9378