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Table 3 Multivariate Cox analysis

From: HPV-16 infection modifies overall survival of Puerto Rican HNSCC patients

Covariate Coefficient Standard error P value HR value, 95 % CI
Positive nodal status 0.308 0.209 0.141 1.361 [0.903 – 2.052]
Tumor stage 0.034 0.099 0.733 1.034 [0.852 – 1.257]
Tumor grade
 Well 0.089 0.442 0.841 1.093 [0.460 – 2.598]
 Moderate 0.348 0.322 0.279 1.417 [0.754 – 2.662]
 Poor 0.496 0.344 0.149 1.642 [0.837 – 3.222]
Tumor site
 Larynx - 0.170 0.337 0.614 0.844 [0.436 – 1.634]
 Oral Cavity - 0.176 0.350 0.616 0.839 [0.423 – 1.665]
 Pharynx 0.237 0.423 0.575 1.267 [0.554 – 2.901]
 Heavy smoking 0.202 0.329 0.539 1.224 [0.642 – 2.333]
 Heavy drinking 0.217 0.249 0.384 1.242 [0.762 – 2.024]
 HPV-16 0.555 0.182 0.002 1.742 [1.219 – 2.488]
 Sex - 0.247 0.324 0.447 0.781 [0.414 – 1.475]
 Age 0.026 0.007 0.000 1.026 [1.011 – 1.041]
  1. (−2 Log Likelihood): 1051.086, HR hazard ratio, 95 % CI 95 % confidence interval, HPV-16 human papillomavirus type 16