Table 2 Nucleotide sequence variations in HPV16 of E6, E7, L1 ORFs, lineage classification and predicted amino acid changes

HPV16Varians

G96A

A131C

T178G

T295G

T350G

A647G

6901-6902

6951-6953

A6989G

Amino acid changes

D25E

D64E

L83V

N29S

448insSer

464delAsp

E Referene

G

A

T

T

T

A

insATC/GTC

delGAT

A

AA

G

A

T

T

G

A

ATC

GAT

A

As

G

A

G

T

T

G

ATC

GAT

A

Af

G

A

T

T

T

A

ATC

GAT

A

Prevalence

XJ-4

EP

No.(%)

ATC

GAT

g

XJ-25

EP

8 (18.6)

ATC

GAT

XJ-28

EP

ATC

GAT

XJ-15

EP

ATC

GAT

XJ-17

EP

ATC

GAT

XJ-31

EP

ATC

GAT

XJ-33

EP

ATC

GAT

XJ-39

EP

ATC

GAT

XJ-1

E-350G

34 (79.1)

G

ATC

GAT

XJ-2

E-350G

G

ATC

GAT

XJ-3

E-350G

G

ATC

GAT

XJ-6

E-350G

G

ATC

GAT

XJ-7

E-350G

G

ATC

GAT

XJ-8

E-350G

a

G

ATC

GAT

XJ-9

E-350G

G

*

*

*

XJ-10

E-350G

G

ATC

GAT

XJ-11

E-350G

G

GTC

GAT

XJ-12

E-350G

G

ATC

GAT

XJ-14

E-350G

G

ATC

GAT

XJ-16

E-350G

G

ATC

GAT

XJ-18

E-350G

G

ATC

GAT

XJ-20

E-350G

G

ATC

GAT

XJ-21

E-350G

G

ATC

GAT

XJ-22

E-350G

G

ATC

GAT

XJ-24

E-350G

G

ATC

GAT

XJ-29

E-350G

G

ATC

GAT

XJ-31

E-350G

G

ATC

GAT

XJ-32

E-350G

G

ATC

GAT

XJ-34

E-350G

G

*

*

*

XJ-36

E-350G

G

ATC

GAT

XJ-37

E-350G

G

ATC

GAT

XJ-38

E-350G

G

ATC

GAT

XJ-40

E-350G

G

*

*

*

XJ-41

E-350G

G

ATC

GAT

XJ-42

E-350G

G

ATC

GAT

XJ-43

E-350G

G

ATC

GAT

XJ-13

E-350G

G

G

ATC

GAT

XJ-19

E-350G

G

G

ATC

GAT

XJ-23

E-350G

G

G

ATC

GAT

XJ-27

E-350G

G

G

ATC

GAT

XJ-30

E-350G

G

G

ATC

GAT

XJ-35

E-350G

G

G

ATC

GAT

XJ-5

AS

1 (2.3)

c

G

ATC

GAT

Mutation

Prevalence (%)

2.3

2.3

2.3

14.0

79.1

100

100

2.4