Table 2 Effects of RFA on the progression of residual HCC in VX2 rabbit model of liver cancer
From: Radio-frequency ablation-based studies on VX2rabbit models for HCC treatment
Animal model | Treatment | Effects on the progression of residual HCC | References |
|---|---|---|---|
Rabbit VX2 HCC model | RFA at different temperatures (55,70 and 85 °C) | Low temperatures induce rapid progression of residual HCC. Tumor progression is associated to PCNA, MMP-9, and VEGF, HGF and IL-6 overexpression. | [18] |
Rabbit VX2 HCC model | Aspirin, RFA | Reduced progression of residual HCC associated to reduced inflammation. | [21] |