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Table 2 Effects of RFA on the progression of residual HCC in VX2 rabbit model of liver cancer

From: Radio-frequency ablation-based studies on VX2rabbit models for HCC treatment

Animal model Treatment Effects on the progression of residual HCC References
Rabbit VX2 HCC model RFA at different temperatures (55,70 and 85 °C) Low temperatures induce rapid progression of residual HCC. Tumor progression is associated to PCNA, MMP-9, and VEGF, HGF and IL-6 overexpression. [18]
Rabbit VX2 HCC model Aspirin, RFA Reduced progression of residual HCC associated to reduced inflammation. [21]