Table 4 p16INK4a levels by immunohistochemistry among HPV positive and negative HNSCC
HPV DNA positive | HPV DNA negative | |||||
|---|---|---|---|---|---|---|
p16 neg | p16 low | p16 high | p16 neg | p16 low | p16 high | |
n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | |
FCMSCSP | ||||||
total | 14 (70.0) | 3 (15.0) | 3 (15.0) | 49 (66.2) | 22 (29.7) | 3 (4.1) |
oral cavity | 4 (100.0) | 0 (0) | 0 (0) | 9 (56.3) | 7 (43.7) | 0 (0) |
oropharynx | 0 (0) | 0 (0) | 1 (100.0) | 5 (55.6) | 3 (33.3) | 1 (11.1) |
larynx | 5 (62.5) | 1 (12.5) | 2 (25.0) | 35 (71.4) | 12 (24.5) | 2 (4.1) |
ICESP | ||||||
total | 14 (66.7) | 2 (9.5) | 5 (23.8) | 60 (91.0) | 5 (7.5) | 1 (1.5) |
oral cavity | 13 (76.4) | 2 (11.8) | 2 (11.8) | 42 (89.3) | 4 (8.5) | 1 (2.2) |
oropharynx | 1 (33.3) | 0 (0) | 2 (66.7) | 12 (92.3) | 1 (7.7) | 0 (0) |
larynx | 0 (0) | 0 (0) | 1 (100.0) | 6 (100.0) | 0 (0) | 0 (0) |