Table 3 Concordant prevalence in patient-partner pairs for oncogenic HPV and genotypes with segregation by tumor HPV status and sex*
From: Concordance of oral HPV prevalence between patients with oropharyngeal cancer and their partners
HPV swab PCR result | All patient-partner pairs (N = 198) | HPV-negative tumor patient-partner pairs (N = 16) | HPV-positive tumor patient-partner pairs (N = 128) | ||||||
|---|---|---|---|---|---|---|---|---|---|
Concordant +, N (%) | Concordant -, N (%) | Discordant, N (%) | Concordant +, N (%) | Concordant -, N (%) | Discordant, N (%) | Concordant +, N (%) | Concordant -, N (%) | Discordant, N (%) | |
High-risk HPV | 19 (9.6) | 159 (80.3) | 20 (10.1) | 1 (6.3) | 13 (81.3) | 2 (12.5) | 10 (7.8) | 106 (82.8) | 12 (9.4) |
HPV16 | 11 (5.6) | 180 (90.9) | 7 (3.5) | 0 (0.0) | 15 (93.8) | 1 P (6.3) | 5 (3.9) | 119 (93.0) | 4 (3.1) |
HPV18 | 2 (1.0) | 195 (98.5) | 1 (0.5) | 1 (6.3) | 15 (93.8) | 0 (0.0) | 1 (0.8) | 127 (99.2) | 0 (0.0) |
HPV31 | 0 (0.0) | 196 (99.0) | 2 (1.0) | 0 (0.0) | 15 (93.8) | 1 P (6.3) | 0 (0.0) | 127 (99.2) | 1 (0.8) |
HPV39 | 0 (0.0) | 197 (99.5) | 0 (0.0) | 1 (6.3) | 15 (93.8) | 0 (0.0) | 0 (0.0) | 128 (100.0) | 0 (0.0) |
HPV43 | 0 (0.0) | 197 (99.5) | 1S (0.5) | 0 (0.0) | 16 (100) | 0 (0.0) | 0 (0.0) | 127 (99.2) | 1 (0.8) |
HPV45 | 0 (0.0) | 193 (97.5) | 5 (2.5) | 0 (0.0) | 16 (100) | 0 (0.0) | 0 (0.0) | 126 (98.4) | 2 (1.6) |
HPV51 | 0 (0.0) | 197 (99.5) | 1 P (0.5) | 0 (0.0) | 16 (100) | 0 (0.0) | 0 (0.0) | 128 (100.0) | 0 (0.0) |
HPV52 | 0 (0.0) | 195 (98.5) | 3 S (1.5) | 0 (0.0) | 16 (100) | 0 (0.0) | 0 (0.0) | 126 (98.4) | 2 (1.6) |
HPV54 | 0 (0.0) | 195 (98.5) | 3 (1.5) | 0 (0.0) | 16 (100) | 0 (0.0) | 0 (0.0) | 126 (98.4) | 2 (1.6) |
HPV56 | 8 (4.0) | 177 (89.4) | 13 (6.6) | 0 (0.0) | 14 (87.5) | 2 (12.5) | 5 (3.9) | 115 (89.8) | 8 (6.2) |
HPV59 | 2 (1.0) | 194 (98.0) | 2 (1.0) | 0 (0.0) | 16 (100) | 0 (0.0) | 1 (0.8) | 126 (98.4) | 1 (0.8) |
HPV61 | 0 (0.0) | 195 (98.5) | 3 (1.5) | 0 (0.0) | 16 (100) | 0 (0.0) | 0 (0.0) | 126 (98.4) | 2 (1.6) |
HPV67 | 1 (0.5) | 194 (98.0) | 3 (1.5) | 0 (0.0) | 16 (100) | 0 (0.0) | 0 (0.0) | 126 (98.4) | 0 (0.0) |
HPV70 | 0 (0.0) | 197 (99.5) | 1 S (0.5) | 0 (0.0) | 16 (100) | 0 (0.0) | 0 (0.0) | 128 (100.0) | 0 (0.0) |
HPV84 | 0 (0.0) | 195 (98.5) | 3 S (1.5) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 128 (100.0) | 0 (0.0) |
Multiple types (≥2) | 9 (4.6) | 176 (88.9) | 13 (6.6) | 1 (6.3) | 14 (87.5) | 1 (6.3) | 3 (2.3) | 118 (92.2) | 7 (5.5) |
Female partners of male patients | |||||||||
N = 160 | N = 13 | N = 101 | |||||||
Concordant +, N (%) | Concordant -, N (%) | Discordant, N (%) | Concordant +, N (%) | Concordant -, N (%) | Discordant, N (%) | Concordant +, N (%) | Concordant -, N (%) | Discordant, N (%) | |
High-risk HPV | 15 (9.4) | 126 (78.8) | 19 (11.9) | 1 (7.7) | 10 (76.9) | 2 (15.3) | 9 (8.9) | 81 (80.2) | 11 (10.9) |
HPV16 | 9 (5.6) | 145 (90.6) | 6 (3.8) | 0 (0.0) | 12 (92.3) | 1 P (7.7) | 5 (5.0) | 93 (92.1) | 3 (3.0) |
Other HPV types | 12 (7.5) | 128 (80.0) | 20 (12.58) | 1 (7.7) | 10 (76.9) | 2 (15.3) | 7 (6.9) | 82 (81.2) | 12 (11.9) |
Multiple types (≥2) | 7 (4.4) | 141 (88.1) | 12 (7.5) | 1 (7.7) | 11 (84.6) | 1 (7.7) | 3 (3.0) | 92 (91.1) | 6 (5.9) |