Table 1 Prevalence of HPV in oral mouth swabs from partners and patients, stratified by tumor HPV status and sex
From: Concordance of oral HPV prevalence between patients with oropharyngeal cancer and their partners
HPV mouth swab PCR result | All patient-partner pairs (N = 198) | HPV-negative tumor patient-partner pairs (N = 16) | HPV-positive tumor patient-partner pairs (N = 128) | ||||||
|---|---|---|---|---|---|---|---|---|---|
Partners, N (%a) | Patients, N (%) | P* | Partners, N (%) | Patients, N (%) | P* | Partners, N (%) | Patients, N (%) | P* | |
All negative | 168 (84.9) | 170 (85.9) | 14 (87.5) | 14 (87.5) | 111 (86.7) | 113 (88.3) | |||
Oncogenic HPV positive | 30 (15.2) | 28 (14.1) | 0.66 | 2 (12.5) | 2 (12.5) | 1.00 | 17 (13.3) | 15 (11.7) | 0.77 |
HPV16 positive | 12 (6.1) | 17 (8.6) | 0.13 | 0 (0.0) | 1 (6.3) | NA | 5 (3.9) | 9 (7.0) | 0.13 |
Other HPV genotype positive | 27 (13.6) | 26 (13.1) | 0.83 | 2 (12.5) | 2 (12.5) | 1.00 | 15 (11.7) | 14 (10.9) | 0.78 |
Multiple (≥2) genotypes positive | 14 (7.1) | 17 (8.6) | 0.58 | 1 (6.3) | 2 (12.5) | 1.00 | 5 (3.9) | 8 (6.3) | 0.45 |
Female partners and male patients | |||||||||
HPV mouth swab PCR result | All male patient-female partner pairs (N = 160) | HPV-negative tumor male patient-female partner pairs (N = 13) | HPV-positive tumor male patient-female partner pairs (N = 101) | ||||||
Partners, N (%a) | Patients, N (%) | P* | Partners, N (%) | Patients, N (%) | P* | Partners, N (%) | Patients, N (%) | P* | |
All negative | 134 (83.8) | 137 (85.6) | 11 (84.6) | 11 (84.6) | 85 (84.2) | 88 (87.1) | |||
Oncogenic HPV positive | 26 (16.3) | 23 (14.4) | 0.49 | 2 (15.4) | 2 (15.4) | 1.00 | 16 (15.8) | 13 (12.9) | 0.55 |
HPV16 positive | 10 (6.3) | 14 (8.8) | 0.22 | 0 (0.0) | 1 (7.7) | NA | 5 (5.0) | 8 (7.9) | 0.25 |
Other HPV genotype positive | 23 (14.4) | 21 (13.1) | 0.65 | 2 (15.4) | 2 (15.4) | 1.00 | 14 (13.9) | 12 (11.9) | 0.56 |
Multiple (≥2) genotypes positive | 12 (7.5) | 14 (8.8) | 0.77 | 1 (7.7) | 2 (15.4) | 1.00 | 5 (5.0) | 7 (6.9) | 0.69 |