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Table 1 Prevalence of HPV in oral mouth swabs from partners and patients, stratified by tumor HPV status and sex

From: Concordance of oral HPV prevalence between patients with oropharyngeal cancer and their partners

HPV mouth swab PCR result All patient-partner pairs (N = 198) HPV-negative tumor patient-partner pairs (N = 16) HPV-positive tumor patient-partner pairs (N = 128)
Partners, N (%a) Patients, N (%) P* Partners, N (%) Patients, N (%) P* Partners, N (%) Patients, N (%) P*
All negative 168 (84.9) 170 (85.9)   14 (87.5) 14 (87.5)   111 (86.7) 113 (88.3)  
Oncogenic HPV positive 30 (15.2) 28 (14.1) 0.66 2 (12.5) 2 (12.5) 1.00 17 (13.3) 15 (11.7) 0.77
HPV16 positive 12 (6.1) 17 (8.6) 0.13 0 (0.0) 1 (6.3) NA 5 (3.9) 9 (7.0) 0.13
Other HPV genotype positive 27 (13.6) 26 (13.1) 0.83 2 (12.5) 2 (12.5) 1.00 15 (11.7) 14 (10.9) 0.78
Multiple (≥2) genotypes positive 14 (7.1) 17 (8.6) 0.58 1 (6.3) 2 (12.5) 1.00 5 (3.9) 8 (6.3) 0.45
Female partners and male patients
HPV mouth swab PCR result All male patient-female partner pairs (N = 160) HPV-negative tumor male patient-female partner pairs (N = 13) HPV-positive tumor male patient-female partner pairs (N = 101)
Partners, N (%a) Patients, N (%) P* Partners, N (%) Patients, N (%) P* Partners, N (%) Patients, N (%) P*
All negative 134 (83.8) 137 (85.6)   11 (84.6) 11 (84.6)   85 (84.2) 88 (87.1)  
Oncogenic HPV positive 26 (16.3) 23 (14.4) 0.49 2 (15.4) 2 (15.4) 1.00 16 (15.8) 13 (12.9) 0.55
HPV16 positive 10 (6.3) 14 (8.8) 0.22 0 (0.0) 1 (7.7) NA 5 (5.0) 8 (7.9) 0.25
Other HPV genotype positive 23 (14.4) 21 (13.1) 0.65 2 (15.4) 2 (15.4) 1.00 14 (13.9) 12 (11.9) 0.56
Multiple (≥2) genotypes positive 12 (7.5) 14 (8.8) 0.77 1 (7.7) 2 (15.4) 1.00 5 (5.0) 7 (6.9) 0.69
  1. *McNemar test (asymptotic or exact)
  2. aDenominators of all the percentages are the corresponding Ns in parentheses
  3. NA = not assessed