Use of swabs for dry collection of self-samples to detect human papillomavirus among Malagasy women

Table 1 Agreement between cobas and H28 for HPV-DNA detection by type categories

Results cobas/H28	HPV distribution by type categories
N (%)	Any hrHPV^a	HPV16/18^b	Pool: 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68
Pos/Pos	112	20	97
Pos/Neg	16	5	15
Neg/Pos	24	5	22
Neg/Neg	245	367	263
Total	397	397	397
Kappa (95 % CI)	0.77 (0.71–0.84)	0.79 (0.66–0.92)	0.77 (0.71–0.84)
% Total Agreement	89.9	97.5	90.7
% Positive Agreement^c	84.8	80.0	84.0
P value	<0.001	<0.001	<0.001

Abbreviations: H28 Seegene Anyplex™ II HPV28, Pos Positive, Neg Negative, N number
^aAny high-risk HPV: HPV 16 and/or HPV18 and/or HPV 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68
^bHPV16/18: HPV16 and or HPV18
^cThe proportion of positive agreement between paired cobas and H28 samples was calculated using 2a/(f1 + g1), where a is the number of samples that were positive for HPV in both tests, f1 is the number of samples that were positive for cobas, and g1 is the number of samples that were positive for H28

ISSN: 1750-9378