Skip to main content

Table 1 Agreement between cobas and H28 for HPV-DNA detection by type categories

From: Use of swabs for dry collection of self-samples to detect human papillomavirus among Malagasy women

Results cobas/H28 HPV distribution by type categories
N (%) Any hrHPVa HPV16/18b Pool: 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68
Pos/Pos 112 20 97
Pos/Neg 16 5 15
Neg/Pos 24 5 22
Neg/Neg 245 367 263
Total 397 397 397
Kappa (95 % CI) 0.77 (0.71–0.84) 0.79 (0.66–0.92) 0.77 (0.71–0.84)
% Total Agreement 89.9 97.5 90.7
% Positive Agreementc 84.8 80.0 84.0
P value <0.001 <0.001 <0.001
  1. Abbreviations: H28 Seegene Anyplex™ II HPV28, Pos Positive, Neg Negative, N number
  2. aAny high-risk HPV: HPV 16 and/or HPV18 and/or HPV 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68
  3. bHPV16/18: HPV16 and or HPV18
  4. cThe proportion of positive agreement between paired cobas and H28 samples was calculated using 2a/(f1 + g1), where a is the number of samples that were positive for HPV in both tests, f1 is the number of samples that were positive for cobas, and g1 is the number of samples that were positive for H28