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Table 1 Patient baseline characteristics at the initiation of antiviral treatment

From: Influence of insulin resistance on the development of hepatocellular carcinoma after antiviral treatment for non-cirrhotic patients with chronic hepatitis C

Baseline characteristics

 

Patient number

474

Age (years)

58 (50–64)

Male, n (%)

230 (48.5)

Body mass index (kg/m2)

23.1 (21.0–25.3)

Alanine aminotransferase (U/L)

52 (33–81)

Total cholesterol (mg/dL)

174 (152–197)

α-fetoprotein (ng/mL)

4.1 (2.5–7.2)

Platelet count (×109/L)

160 (125–199)

Hemoglobin A1c (NGSP) (%)

5.5 (5.3–5.9)

Fasting plasma glucose (mg/dL)

93 (87–101)

Fasting serum insulin (μU/mL)

8.6 (5.9–13.7)

HOMA-IR

1.9 (1.3–3.3)

HCV RNA level (logIU/mL)

6.2 (5.7–6.6)

HCV genotype, n (%)

 1a

4 (0.8)

 1b

360 (75.9)

 2a

63 (13.3)

 2b

47 (9.9)

Fibrosis stage, n (%)

 F0-1

241 (50.8)

 F2

104 (21.9)

 F3

76 (16.0)

 Not determined

53 (11.2)

Activity grade, n (%)

 A0-1

162 (34.2)

 A2

244 (51.5)

 A3

15 (3.2)

 Not determined

53 (11.2)

  1. Data expressed as number (%) or median (first-third quartiles)
  2. HOMA-IR, homeostasis model assessment of insulin resistance; HCV hepatitis C virus