Table 5 Association between the presence of P. gingivalis or Lys-gingipain and the clinicopathologic features of ESCC patients
Factors | Pg positive cases (%) | KGP positive cases (%) |
|---|---|---|
ESCC samples (n = 100) | 61(61)** | 66(66)** |
Adjacent normal tissues (n = 100) | 12(12)** | 17(17)** |
Normal esophageal mucosa (n = 30) | 0(0)** | 0(0)** |
Gender | ||
Male (n = 70) | 45(64.3) | 48(68.6) |
Female (n = 30) | 16(53.3) | 18(60.0) |
Age (years) | ||
≤60 (n = 39) | 24(61.5) | 23(59.0) |
>60 (n = 61) | 37(60.7) | 43(70.5) |
Smoking history | ||
Smoking (n = 45) | 31(68.9) | 32(71.1) |
Non-smoking (n = 55) | 30(54.5) | 34(61.8) |
Differentiation | ||
Well (n = 22) | 8(36.4)* | 10(45.5)* |
Moderate (n = 58) | 35(60.3)* | 39(67.2)* |
Poor (n = 20) | 18(90.0)* | 17(85.0)* |
Lymph node metastasis | ||
Positive (n = 38) | 32(84.2)* | 31(81.6)* |
Negative (n = 62) | 29(46.8)* | 35(56.5)* |
TNM stage | ||
I+ II (n = 68) | 33(48.5)* | 39(57.4)* |
III (n = 32) | 28(87.5)* | 27 (84.4)* |