| | | |
Sensitivity
|
Specificity
|
PPV
|
NPV
|
|---|
|
Lesion
|
Age
|
[n lesions]
|
% (95 % CI)
|
|---|
|
CIN2+
|
<30
|
[24]
|
62.5
|
54.7
|
16.1
|
91.3
|
| | | |
(40.6–81.2)
|
(46.9–62.2)
|
(9.3–25.2)
|
(84.1–95.9)
|
| |
≥30
|
[63]
|
54.0
|
66.3
|
16.4
|
92.2
|
| | | |
(40.9–66.6)
|
(62.1–70.4)
|
(11.6–22.1)
|
(89.0–94.7)
|
| |
All
|
[87]
|
56.3
|
63.4
|
16.3
|
92.0
|
| | | |
(45.9–66.7)
|
(59.8–67.0)
|
(12.1–20.4)
|
(89.6–94.4)
|
|
CIN3+
|
<30
|
[11]
|
81.8
|
54.6
|
9.7
|
98.1
|
| | | |
(48.2–97.7)
|
(47.1–61.9)
|
(4.5–17.6)
|
(93.2–99.8)
|
| |
≥30
|
[39]
|
64.1
|
66.2
|
12.0
|
96.2
|
| | | |
(47.2–78.8)
|
(62.0–70.1)
|
(7.9–17.2)
|
(93.7–97.9)
|
| |
All
|
[50]
|
68.0
|
63.2
|
11.3
|
96.6
|
| | | |
(55.1–80.9)
|
(59.7–66.7)
|
(7.7–14.9)
|
(95.0–98.3)
|
-
CIN2+ cervical intraepithelial neoplasia grade 2 or worse; CIN3+ cervical intraepithelial neoplasia grade 3 or worse; PPV positive predictive value; NPV negative predictive value
