Fig. 3
From: miR-23b as a potential tumor suppressor and its regulation by DNA methylation in cervical cancer
Differential mRNA expression of uPa, c-Met and Zeb1 in cervical cancer cell lines treated with 5′-Aza-CdR. a Hybridization sequences between miR-23b and its potential target mRNAs. b After treatment with 5′-Aza-CdR, the mRNA expression level of uPa decreased in C33A and CaSki cells. c The expression of c-Met decreased in C33A, CaSki and HeLa cells after exposure to 5′-Aza-CdR and the changes in HeLa cells were significant. d Treatment with 5′- Aza-CdR significantly decreased Zeb1 expression levels in C33A and CaSki cells. The mRNA expression levels of GAPDH were used to normalize the data. *Statistically significant difference (p < 0.05); W/T: Untreated cells