Fig. 1
From: miR-23b as a potential tumor suppressor and its regulation by DNA methylation in cervical cancer
Regulatory elements for the expression of miR-23b. a The diagram shows putative p53-binding sites in the miR-23b promoter. The yellow box represents the location of miR-23b precursor, and the green box symbolizes a binding site for p53 [22]. The pink boxes indicate putative binding sites for p53 [22, 23]. b CpG islands in the promoter region of miR-23b (blue boxes). The region containing CpG islands was amplified in this study to determine the methylation status of miR-23b promoter