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Table 3 HPV prevalence in breast cancer cases by detection method and histological type

From: Inconclusive role of human papillomavirus infection in breast cancer

Variable No. of studies No. of cases HPV prevalence (%) (95 % CI)
Detection method    
PCR-based method 37 2415 31.30(22.60–39.90)
Broad-spectrum primers 20 1102 30.00(18.30–41.70)
Type-specific primers 9 481 31.90(13.00–50.80)
Combined primers 8 832 35.30(11.50–59.00)
Non-PCR-based methoda 6 466 5.30(2.40–8.30)
Histological type    
IDC 27 1536 32.90(21.50–44.20)
Otherb 21 329 22.00(12.40–31.50)
  1. CI confidence interval, PCR polymerase chain reaction, IDC invasive ductal carcinomas
  2. aOthers included in situ hybridization and Southern blotting
  3. bOthers included ductal carcinoma in situ, intraductal papilloma, medullary carcinoma, and mixed or unclear histological types