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Table 1 Schematic representation of the relative changes in oncoproteins or Tumor suppressor proteins, and microRNAs in HCV-infected HCC negative (N) and liver tumors (T) as compared with the control liver (derived from the results shown in Figs. 1, 2, 3, 4 and 5).

From: HCV infection-associated hepatocellular carcinoma in humanized mice

  

Levels

 

Category

Control

HCC(Neg)

HCC

Tumor Suppressor

   

PTEN(N)

+++

++

++/+

PTEN (C )

+++

++

++/+

DLC1

+++

++

+

p21

++

++

+

 Oncoprotein

   

p-AKT

++

++

+++

CyclinD1

+

+++

+++

c-myc

+

+

+++

STAT3

+

+

+++

 OncomiR

   

miR-141

++

+

++++

miR-221

+

+

+++

miR-21

+

+

+++

 Tumor Suppressor(miRNA)

   

miR-26a

++

+++

+