Fig. 2
From: Viral non-coding RNA inhibits HNF4α expression in HCV associated hepatocellular carcinoma
Altered expression of Vimentin and EMT markers in liver tumors of HCV-infected MUP-uPA/SCID/Bg mice: ( 2a ) Induction of Vimentin in liver tumor was compared to the liver tissue from human hepatocyte engrafted but uninfected chimeric mice. Representative Western blots of four tumors and four control liver is shown in the upper panel with β-Actin loading control. Lower panel shows relative increase in Vimentin in liver tumors was compared to the uninfected controls. ( 2b) Expression levels of EMT regulatory genes in liver tumors. Liver protein from seven uninfected controls and eight HCV infected humanized mice were compared by Western blotting (run in triplicate); Relative values (Mean +/- SE, normalized to β-Actin loading control) of each protein is given underneath