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Table 2 Main data and principal performance indicators of seven Italian pilot programmes adopting HPV as primary screening test followed by cytology triage, by country of birth
| Relative risk immigrants vs. Italians | ||||||||
|---|---|---|---|---|---|---|---|---|
| Italy-born | Born abroad | Crude RR | 95% CI | Age adjusted RR | 95% CI | |||
| N | (%)* | N | (%)* | |||||
| Invited Population (N) | 140,015 | 22,814 | ||||||
| Undelivered letters | 1,305 | 0.9 | 1196 | 5.2 | ||||
| Participants | 73,023 | 52.2 | 9941 | 43.6 | 0.84 | (0.82-0.85) | ||
| Participation excluding undelivered letters (%) | 52.6 | 46.0 | 0.87 | (0.86-0.89) | ||||
| HPV tests performed | 72,176 | 9680 | ||||||
| HPV positive | 4,421 | 6.1 | 751 | 7.8 | 1.27 | (1.18-1.36) | 1.18 | (1.13-1.22) |
| cytological triage* | ||||||||
| Negative | 1,925 | 48.4 | 326 | 49.2 | ||||
| Inadequate | 180 | 4.5 | 24 | 3.6 | ||||
| ASC-US | 444 | 11.2 | 66 | 10.0 | ||||
| AGC | 17 | 0.4 | 5 | 0.8 | ||||
| L-SIL | 1,173 | 29.5 | 174 | 26.3 | ||||
| ASC-H | 74 | 1.9 | 22 | 3.3 | ||||
| H-SIL | 158 | 4.0 | 42 | 6.3 | ||||
| Cancer | 3 | 0.1 | 3 | 0.5 | ||||
| Total ASC-US+ (% of HPV positive) | 1,869 | 47.0 | 312 | 47.1 | 0.98 | (0.87-1.07) | 0.95 | (0.90-0.99) |
| Referred to colposcopy | 1,968 | 2.7 | 324 | 3.3 | 1.23 | (1.09-1.38) | 1.22 | (1.09-1.37) |
| Compliance to colposcopy | 1,840 | 93.5 | 297 | 91.7 | 0.98 | (0.95-1.02) | ||
| Detection rate for CIN3+ (‰ screened women) | 163 | 2.3 | 50 | 5.2 | 2.29 | (1.67-3.14) | 2.29 | (1.90-2.75) |
| Detection rate for CIN2+ (‰ screened women) | 342 | 4.7 | 79 | 8.2 | 1.72 | (1.35-2.20) | 1.65 | (1.45-1.89) |
| CIN2 | 179 | 52.3 | 29 | 36.7 | ||||
| CIN3 + adeno in situ | 153 | 44.7 | 45 | 56.7 | ||||
| Invasive Cancer | 10 | 5.6 | 5 | 17.2 | 3.73 | (1.27-10.90) | 3.9 | (1.33-11.41) |
| Positive predictive value of colposcopy referral | 18.6 | 26.6 | 1.43 | (1.16-1.77) | 1.38 | (1.12-1.71) | ||
