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Table 1 Association of OPC with prevalence of anti-HPV IgG antibodies in a Sri Lankan study population

From: A shifting paradigm in the aetiology of oral and pharyngeal cancer in Sri Lanka: a case-control study providing serologic evidence for the role of oncogenic HPV types 16 and 18

Characteristic

OPC cases (N = 78)

Controls (N = 51)

Chi-square

P - value

Unadjusted odds ratio (95% CI)

HPV16/18 L1 serologic status

     

Seronegative

42 (53.8%)

48 (94.12%)

  

1.0

Seropositive

36 (46%)

3 (5.88)

21.84

0.00

13.714(3.935-7.795)

HPV16L1 serologic status

     

Seronegative

60 (76.9%)

48 (94.1%)

  

1.0

Seropositive

18 (23.1%)

3 (5.8%)

5.487

0.019

4.8 (1.335-17.261)

HPV18 L1 serologic status

     

Seronegative

53 (68%)

50 (98.04%)

  

1.0

Seropositive

25 (32%)

1 (1.96%)

15.531

0.00

23.56(3.08-180.620)