Figure 6
From: Escherichia coli-derived outer membrane vesicles are genotoxic to human enterocyte-like cells
O157:H7 E. coli induce cell cycle changes in LoVo cells. LoVo cells were exposed to OMVs for 4 days, before being subjected to cell cycle analysis. O157:H7 OMV induced a dose dependent G1 arrest. *, results are significantly different from untreated controls (p ≤ 0.05). ANOVA, followed by two-sided Dunnet’s post hoc test. Results are ± SEM of three independent experiments.