High viral load of Merkel cell polyomavirus DNA sequences in Langerhans cell sarcoma tissues

Table 1 Clinical characteristics and lesional MCPyV data of patients with LCS

Patient	Age (years)	Sex	Tissue	Q-PCR (Viral load)*	MCPyV large T antigen (CM2B4)
LCS1	81	F	Skin	-	-
LCS2	73	M	LN	-	-
LCS3	72	F	Salivary gland	+ (0.453)	-
LCS4	61	M	Lung	+ (0.772)	-
LCS5	62	M	LN	+ (0.328)	-
LCS6	40	M	LN	-	-
LCS7	81	F	LN	-	-

The median age of the LCS patients (n = 7) was 72 years (range, 42–81 years of age). *Positive control (MCC):+ (Viral load = 1.0), Negative control (double distilled water): −. Viral load, relative levels of MCPyV. Abbreviations: LCS Langerhans cell sarcoma, LN lymph node, MCC Merkel cell carcinoma, MCPyV Merkel cell polyomavirus, Q-PCR multiplex quantitative PCR for MCPyV.

ISSN: 1750-9378