Table 1 Summary of AIDS-associated malignancy studies among adults in Africa, January 2001 – December 2012
Reference | Study type | Study population | Study period | Key findings |
|---|---|---|---|---|
Ocheni (2004) [14] | Case series | University College Hospital, Ibadan, Nigeria | Oct 2001 – June 2002 | KS prevalence = 0.01% |
n = 6; age range =29-35; m:f = 1:1.4 | ||||
CC prevalence = 0.01% | ||||
NHL prevalence = 0.02% | ||||
Cisse (2007) [15] | Case series | Hôpital du Point G, Bamako, Mali | Oct 2004 – Sept 2005 | KS prevalence = 1.6% |
n = 37; mean age = 39.5; m:f = 1:1 | ||||
Ibekwe (2011) [16] | Case series | University college hospital Ibadan, Nigeria | Oct 2008 - Sep 2009 | KS prevalence =0.5% |
n = 13; age range = 26 – 56; m:f = 1:1 | ||||
Abdus-Salam (2006) [17] | Case series | University college hospital Ibadan, Nigeria | 2005- 2007 | CC prevalence = 2.7% |
n = 6 | ||||
Bolarinwa (2009) [18] | Case series | Obafemi Awolowo university teaching hospital, Ile-Ife, Nigeria | Jan 1993 – Aug 2008 | NHL = 1.5% |
n = 9; age range = 24 – 60; m:f = 1:1 | ||||
Chu (2010) [19] | Case series | 3 primary care HIV clinics, Khayelitsha, Cape town, South Africa | May 2001 – Jan 2007 | KS prevalence = 2.4% |
n = 189; age IQR = 29 – 41; m:f = 1.4:1 | ||||
Iregbu (2006) [20] | Case series | National hospital Abuja, Nigeria | Jan 2002 – July 2005 | KS prevalence = 0.8% |
n =15; age = 20–49; m:f = 2:1 | ||||
Sitas (2000) [13] | Case–control | Chris Hani-Baragwanath, Hillbrow, New Johannesburg Hospitals, South Africa | 1995 – 1999 | KS* = 21.9 (12.5, 38.6) |
n CC = 167; n KS = 89; n = NHL = 23 | NHL* = 5.0 (2.7-9.5) | |||
CC* = 1.6 (1.1-2.3) | ||||
Stein (2008) [21] | Case–control | Chris Hani Baragwanath, Hillbrow & New Johannesburg Hospitals, Johannesburg, South Africa | Mar 1995–June 2004 | Age group 18 – 34 only |
n CC = 167; n KS = 89; n NHL = 50 | KS* = 58.6 (27.6, 124.5) | |||
Age range = 18 – 55+ | NH* = 6.6 (3.7, 12.0) | |||
CC* = 1.5 (0.9, 2.4) | ||||
Mbulaiteye (2006) [12] | AIDS cancer registry match | Kampala cancer registry and AIDS support organization, Kyadondo, Uganda | Oct 1998 – Dec 2002 | KS# = 6.4 (4.8-8.4) |
Number of incident cancers = 137; age IQR = 25-35 | NHL# = 6.7 (1.8-17) | |||
CC# = 2.4 (1.1-1.4) | ||||
Chaabna (2011) [22] | Population-based cancer registries | Kyadondo, Uganda; Harare, Zimbabwe; Setif, Algeria; Sousse, Tunisia; and Gharbiah Egypt | 1998 - 2002 | KSP = <0.3– 26.3/100,000 |
CCP = <8-34.8/100,000 | ||||
NHLP = 2.4 – 11.9/100,000 |