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Table 1 Distribution of KIR genes in the Busselton control population and the group of Western Australian women with a history of CIN

From: Human papillomavirus, high-grade intraepithelial neoplasia and killer immunoglogulin-like receptors: a Western Australian cohort study

KIR gene

Cases

Controls

p-valuea

p-value correctedb

Ā 

nā€‰=ā€‰147

nā€‰=ā€‰187

Ā Ā 

2DL1

144 (98.0%)

178 (94.2%)

0.149

1

2DL2

67 (45.6%)

108 (57.1%)

0.046*

0.644

2DL3

136 (92.5%)

170 (89.9%)

0.531

1

2DL4

147 (100%)

189 (100%)

1

1

2DL5

78 (53.1%)

100 (52.9%)

0.978

1

3DL1

133 (90.5%)

177 (93.7%)

0.382

1

3DL2

147 (100%)

189 (100%)

1

1

3DL3

147 (100%)

189 (100%)

1

1

2DS1

58 (39.5%)

76 (40.2%)

0.978

1

2DS2

68 (46.3%)

109 (57.7%)

0.049 *

0.686

2DS3

44 (29.9%)

55 (29.1%)

0.964

1

2DS4 **

55 (37.4%)

77 (40.7%)

0.612

1

2DS5

50 (34.0%)

57 (30.2%)

0.526

1

3DS1

61 (41.5%)

78 (41.3%)

0.967

1

  1. CIN, Cervical intraepithelial neoplasia; KIR, Killer immunoglobulin-like receptor.
  2. aĻ‡2 test with Yates correction was performed; p-valuesā€‰<ā€‰0.05 are indicated in bold for Ļ‡2 test.
  3. bCorrected p-values were determined by adjusting p-values for multi-gene analysis using Bonferroniā€™s correction.
  4. *ORā€‰=ā€‰0.6; 95% CI 0.4 ā€“ 0.9.
  5. **2DS4 psuedogenes not counted.