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Table 1 Distribution of KIR genes in the Busselton control population and the group of Western Australian women with a history of CIN

From: Human papillomavirus, high-grade intraepithelial neoplasia and killer immunoglogulin-like receptors: a Western Australian cohort study

KIR gene Cases Controls p-valuea p-value correctedb
  n = 147 n = 187   
2DL1 144 (98.0%) 178 (94.2%) 0.149 1
2DL2 67 (45.6%) 108 (57.1%) 0.046* 0.644
2DL3 136 (92.5%) 170 (89.9%) 0.531 1
2DL4 147 (100%) 189 (100%) 1 1
2DL5 78 (53.1%) 100 (52.9%) 0.978 1
3DL1 133 (90.5%) 177 (93.7%) 0.382 1
3DL2 147 (100%) 189 (100%) 1 1
3DL3 147 (100%) 189 (100%) 1 1
2DS1 58 (39.5%) 76 (40.2%) 0.978 1
2DS2 68 (46.3%) 109 (57.7%) 0.049 * 0.686
2DS3 44 (29.9%) 55 (29.1%) 0.964 1
2DS4 ** 55 (37.4%) 77 (40.7%) 0.612 1
2DS5 50 (34.0%) 57 (30.2%) 0.526 1
3DS1 61 (41.5%) 78 (41.3%) 0.967 1
  1. CIN, Cervical intraepithelial neoplasia; KIR, Killer immunoglobulin-like receptor.
  2. aχ2 test with Yates correction was performed; p-values < 0.05 are indicated in bold for χ2 test.
  3. bCorrected p-values were determined by adjusting p-values for multi-gene analysis using Bonferroni’s correction.
  4. *OR = 0.6; 95% CI 0.4 – 0.9.
  5. **2DS4 psuedogenes not counted.