Table 4 Odds ratio of the HLA-DRB1 alleles found associated in the studied groups
Control group | Case group | Class II allele | p value, OR and CI 95% |
|---|---|---|---|
HPV-reinfected | HPV-persistent | DRB1*04 | 0.02, OR 8.8 (1.0 -196) |
Healthy individuals | HPV-cleared | DRB1*07 | 0.04, OR 2.8 (1.03 -8.3) |
Healthy individuals | HPV-persistent + reinfected + cleared | DRB1*07 | 0.04, OR 2.7 (1.03 -7.2) |
HPV-cleared | HPV-persistent + cervical cancer | DRB1*07 | 0.05, OR 0.45 (0.20-1.02) n.s. |
HPV-cleared + HPV-reinfected | HPV-persistent + cervical cancer | DRB1*07 | 0.03, OR 0.42 (0.19-0.89) |
Healthy individuals | HPV-persistent + cervical cancer | DRB1*07 | 0.01, OR 0.31 (0.12-0.79) |
Healthy individuals | HPV-persistent + reinfected | DRB1*10 | 0.03, OR 10.9 (1.12 -261) |
Healthy individuals | HPV-reinfected | DRB1*10 | 0.04, OR 14.5 (1.27-167) |
Healthy individuals | HPV-persistent + cervical cancer | DRB1*10 | 0.05, OR 6.53 (0.82-52) n.s. |
Cervical cancer | HPV-persistent | DRB1*14 | 0.07, OR 0.34 (0.11 -1.09) n.s. |